Firefighters were called to the scene on Atlantic Avenue just after 7:30 a.m. Saturday.
Video from Citizen App showed heavy smoke and flames pouring out of the building in Cypress Hills Saturday morning.
Eyewitness News is told the fire started in a single-story auto repair shop.
The roof partially collapsed after firefighters arrived and began working to control the blaze.
Three firefighters were being treated for injuries described as minor sprains and strains.
The cause of the fire is under investigation.
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