Sophie, 58, opted for a dark brown trouser suit by Gabriela Hearst for the final day of her trip, which kicked off last Friday.
Her Royal Highness, who took part in several exercises during her tour, met with frontline healthcare workers, researchers and patients to learn more about the medical innovations at University Health Network (UHN).
Sophie’s visit to various hospitals over the past few days was intended to share advancements in arthritis, vision and brain research, social and emergency medicine, as well as innovations in cardiovascular care and the latest technologies in physical rehabilitation.
The solo overseas tour is an indication of Sophie’s importance within the Royal Family, after being chosen to visit the largest Commonwealth country – and becoming the first member of the monarchy to do so since the death of Queen Elizabeth II.
For the occasion, Sophie chose a sleek double-breasted blazer and straight-leg trousers by Gabriela Hearst, created in a chocolate brown hue.
She added a floral blouse, also by the New York-based brand, elevating her outfit with court shoes.
The mother-of-two completed her look with a pair of simple gold hoop earrings, while her blonde hair was neatly clipped back.
It comes after the royal visited the Toronto Western Hospital yesterday. Sophie looked delighted to play around with the tech in her role as Patron of Toronto General and Toronto Western hospitals, University Health Network (UHN).
Looking typically elegant, the late Queen’s daughter-in-law opted for a stylish dress and matching boots, while wearing a poppy badge pinned to her ensemble.
The Duchess styled her blonde tresses in a bun and wore a striking make-up, accentuating her eyes with dark mascara.
Adding a touch of glitz to her outfit, she sported a gold necklace and a matching bracelet.
She painted her nails a sophisticated pink colour while carrying a patterned clutch in her hands.
As well as meeting staff at the hospital, the Duchess also posed for a photograph with Elizabeth Dowdeswell, Lieutenant Governor of Ontario and Madame Edith Dumont.
Later that evening, the royal attended a glamorous reception at the Four Seasons Hotel for supporters and staff of the Toronto General and Toronto Western Hospitals.
Sophie was positively glowing as she took to the stage in an eye-catching dress by Etro, which she debuted in July.
The demure navy design incorporated a cinched waist and midi length that was decorated with ornamental floral patterns.
Sophie added Jimmy Choo heels and a Sophie Habsburg clutch in complementary shades.
On Monday, the Duchess paid a visit to Toronto General Hospital, where she appeared in good spirits while chatting to staff.
The £195 dress Sophie chose for the outing incorporated a fit-and-flare silhouette, adorned with the brand’s Romantic Floral motif, which is meticulously screen printed by hand.
She accessorised with a diamond maple leaf pendant by Maison Birks that has been in her personal collection since 2013.